Pixel-programmable miniaturized optical arrays with large pixel count are essential for cutting-edge fields such as micro-displays, photonic chips, and light detection modules. In recent advances, a universal strategy with ultrahigh pixel count and highly flexible programmability remains lacking. Here we report a programmable optical nano-kirigami matrix with pixelated electromechanical reconfigurations. Deformable pixel arrays with high duty cycle and optical contrast are conceptually designed and experimentally realized based on a suspended turn-shaped nano-kirigami configuration. By employing the central plate to induce electrostatic force and the deformed arms to scatter incident light, switchable optical encryption and reconfigurable information display are demonstrated by programing the nano-kirigami matrices with a pitch size of only a few micrometers. Furthermore, line-level modulation based programmable information transmission and light projection are achieved by using a stripe-shaped addressable nano-kirigami matrix with 3.87 megapixels, showcasing an optical micro-array with large pixel count and flexible programmability. Our work enables the high visibility and precise addressability of freely controllable electromechanical arrays with massive pixels, which could greatly improve the practical applicability for miniaturized optical arrays and brings potential applications in micro-displays, photoelectronic chips, intelligent machine visions, hyperspectral image sensors, etc.